In this talk, Prof. Takayama described development and use of aqueous two-phase system (ATPS) droplets for biological assays. Specific topics to be presented include use of ATPS droplet arrays that incorporate immunoassays for analysis of proteins, and ATPS droplet protocell arrays that incorporate in vitro transcription/translation for simultaneous analysis of small molecules, RNA, and DNA. Another topic will be application of ATPS droplets to studies of bacteria communication, biofilm formation, and antibiotic studies. Bacteria-interaction analysis with neutrophil extracellular trap (NET)-mimetic materials will also be presented. Finally, use of ATPS droplet-based bioprinting of fibroblast-extracellular matrix droplets that mimic microscale scars will be presented.
Date: 22 June 2021 (Tue)
Time: 10 – 11am (HKT)
Venue: Online (ZOOM)
Speaker: Prof. Shuichi Takayama, Professor, GRA Eminent Scholar, Price Gilbert, Jr. Chair in Regenerative Engineering and Medicine, The Wallace H. Coulter Dept of Biomedical Engineering, Georgia Institute of Technology & Emory School of Medicine
Moderator: Prof. Anderson Shum, Professor & Associate Head, Department of Mechanical Engineering, The University of Hong Kong
Speaker: Prof. Shuichi Takayama
Title: Professor, GRA Eminent Scholar, Price Gilbert, Jr. Chair in Regenerative Engineering and Medicine, The Wallace H. Coulter Dept of Biomedical Engineering, Georgia Institute of Technology & Emory School of Medicine
- B.S.& M.S., 1986-1994, Agricultural Chemistry, University of Tokyo
- Ph.D., 1994-1998, Scripps Research Institute, Chemistry
- Postdoc 1998-2000 Harvard University, Chemistry and Chemical Biology
Prof. Shuichi Takayama’s research interests started with bioorganic synthesis at the University of Tokyo and Scripps Research Institute. Subsequently he pursued postdoctoral studies in bioengineered microsystems at Harvard University as a Leukemia and Lymphoma Society Fellow. He spent 17 years at the University of Michigan in the Biomedical Engineering Department and Macromolecular Science and Engineering Program, then moved to the Wallace H. Coulter Department of Biomedical Engineering at the Georgia Institute of Technology and Emory School of Medicine in the summer of 2017. He is an associate editor of Integrative Biology and recipient of the Pioneers of Miniaturization Prize.
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